v25i2

July 2020 7 HKUMed uncovers novel DNA repair network as promising cancer drug targets 港大醫學院發現全新 DNA 修復網 絡 以作為癌症藥物新標靶 14 HKUMed researchers mine immunogenic information from SARS-CoV-2 for rational design of vaccine against SARS-CoV-2 港大醫學院深度挖掘新型冠狀病毒 重要免疫原性信息 為疫苗的理性 設計提供依據 16 HKUMed and Institut Pasteur collaborate to use an evolution in a test tube approach to develop new molecules for malaria diagnosis 港大醫學院與法國巴斯德研究所 合作 採用試管演化方式開發新型 分子作瘧疾診斷 3 HKUMed discovers a novel mediator of cerebral ischaemia injury and its underlying mechanism which can be a new therapeutic target for ischaemic stroke 港大醫學院發現一種新的腦缺血 損傷介質及其病理機制 為缺血性 中風治療提供新治療靶點 9 HKUMed researchers reveal the clinical characteristics and epidemiological trend of COVID-19 infected children 港大醫學院揭示感染新型冠狀病毒 兒童的臨床特徵和流行病學趨勢 10 HKU Department of Microbiology ’ s research on subclinical SARS-CoV-2 infection 香港大學微生物學系對 2019 冠狀 病毒隱性患者的研究 16 HKUMed introduced and carried out Asia ’ s first Water Vapour Thermal Therapy for benign prostatic hyperplasia 港大醫學院引入並完成亞洲首宗水 蒸氣熱力治療手術以治療良性前列 腺增生症 17 HKU Department of Microbiology discovers the effectiveness of the combination of RT-PCR and serology in case finding of asymptomatic COVID-19 in the Diamond Princess Cruise Ship 港大醫學院微生物學系證實 結合 核酸檢測和血清檢測更準確發現鑽 石公主號郵輪的無症狀 2019 冠狀 病毒患者 22 HKUMed research suggested that the serial interval of SARS-CoV-2 can be shortened substantially over time by non-pharmaceutical interventions 港大醫學院研究顯示非藥物干預措 施可在一段時間內大幅縮短新型冠 狀病毒（ SARS-CoV-2 ）的間隔時間 24 HKU, Sanford Burnham Prebys Medical Discovery Institute, Scripps Research and Icahn School of Medicine at Mount Sinai jointly discovered highly effective antiSARS-CoV-2 drugs through a large-scale drug repurposing 香港大學、美國桑福德 · 伯納姆 · 普雷比斯醫學發現研究所、斯克里 普斯研究所和西奈山醫學院聯合研 究 利用已知的臨床藥物鑑定高效 能的抗新冠狀病毒藥物 27 HKUMed reveals the pathogenic gene of carpal tunnel syndrome, providing new directions for prevention and treatment 港大醫學院研究揭示腕管綜合症致 病基因 為預防和治療指引新方向 August 2020 4 HKUMed researchers first discovered SARS-CoV-2 infects human neural progenitor cells and brain organoids 港大醫學院研究人員首次發現新型 冠狀病毒感染人類神經祖細胞和 腦類器官 6 HKUMed discovers that acute SARS-CoV-2 infection impairs human immune defences: significant implications for viral transmission, disease severity and vaccine research 港大醫學院發現新型冠狀病毒急性 感染削弱人體免疫防禦：對病毒 傳播、病情加劇和疫苗研究有重要 意義 10 HKUMed finds that an anti- osteoporosis drug is associated with reduced risk of pneumonia in patients with hip fracture 港大醫學院發現髖骨骨折病人服用 骨質疏鬆藥物可減低患染肺炎風險 59 Medical Faculty News