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The world is facing an unprecedented threat from the COVID-19 in 2020. Since the outbreak, the School of Public Health has been working tirelessly to share knowledge-based and evidence-based scientific research and educate students and the public through a series of engaging initiatives. A series of live dialogues were held on March 6, April 3, and May 29, 2020, in which members of the School shared their insights on health diplomacy, response strategies, and health economics and policies, based on their experiences with global outbreaks. Speakers were: Professor Keiji Fukuda ( 福田敬二 ) , Director of the School of Public Health and former Assistant Director-General for Health Security at the World Health Organization (WHO); Professor Benjamin Cowling ( 高本恩 ) , Professor and Head of Division of Epidemiology and Biostatistics and Dr Karen Grépin , Associate Professor, of the School of Public Health. Since April 2020, the School has published the ongoing “Voices from the COVID-19 Frontlines” video series featuring stories of the School's internationally renowned scientists, educators and health economists. A webpage (https://covid19.sph.hku.hk ) was developed by the WHO Collaborating Centre for Infectious Disease Epidemiology and Control to share the latest scientific findings and contextualise the implications to encourage evidence-based public health policies on COVID-19. On March 31, 2020, the School joined with HKU Journalism and Media Studies Centre to co-host a public health workshop for journalists covering the COVID-19 pandemic. The workshop served as a pilot programme, trying to give journalists deeper insight into public health and science. It addressed the basics of infectious diseases and assisted journalists in understanding and interpreting public health information and data. These timely public awareness initiatives helped students and the general public acquire vital knowledge about the coronavirus, contributing to the high level of public awareness and compliance with public health measures in Hong Kong. School of Public Health Contributed in Knowledge Exchange and Raising Public Awareness during COVID-19 Training Course on Study Design & Sample Size Calculation for Investigator-initiated Clinical Studies IIS”), comprising four courses. The first course – Study Design & Sample Size Calculations – was completed by way of an online seminar on August 28, 2020, with great success. Professor Ian Wong Chi-kei ( 黃志基 ) , Head of the Department of Pharmacology and Pharmacy, and Dr Helen Zhi ( 智慧 ) , Director of BCMU, shared their practical tips and experience in designing and managing big data research and clinical trials with over 300 participants. The course received an enthusiastic response. The CTC will continue to organise courses on IISs, and announcements for the next stage will be made via HKU emails and on CTC’s website (https://www.hkuctc.com/) . Investigator-initiated clinical studies (IISs) play an essential role in translating medical discoveries and hypotheses into clinical practice and bringing value to the advancement of human healthcare. To encourage and facilitate more high impact IISs, HKUMed has recently delegated the Clinical Trials Centre (CTC) and the Biostatistics and Clinical Research Methodology Unit (BCMU) to establish an "IIS Facilitation Scheme". A range of support structures and services will be offered to clinical investigators in stages. The first initiative under this scheme is a comprehensive training programme (named “PRACTISE ® 25 Medical Faculty News